Validation of parental reports of asthma trajectory, burden, and risk by using the pediatric asthma control and communication instrument.
Validation of parental reports of asthma trajectory, burden, and risk by using the pediatric asthma control and communication instrument.
复制标题
使用儿科哮喘控制和通讯工具验证家长关于哮喘轨迹、负担和风险的报告。
DOI：
10.1016/j.jaip.2013.10.005
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Patino,CeciliaM
中科院分区：
文献类型：
--
作者：
Okelo,SandeO;Eakin,MichelleN;Riekert,KristinA;Teodoro,AlvinP;Bilderback,AndrewL;Thompson,DarcyA;Loiaza-Martinez,Antonio;Rand,CynthiaS;Thyne,Shannon;Diette,GregoryB;Patino,CeciliaM
背景：尽管人们的兴趣越来越大，但很少有儿科哮喘问卷评估哮喘发病率的多个维度，如国家哮喘指南所推荐的，或使用患者报告的结果。目的对一份测量家长报告哮喘发病率（方向、困扰和风险）的问卷进行评价。方法对接受常规哮喘治疗的儿童进行儿童哮喘控制与沟通仪（PACCI），评估哮喘控制（PACCI Control）、生活质量和肺功能。对PACCI进行判别效度评估。结果共有317名儿童参与，平均年龄8.2岁，其中58%为男孩，44%为非裔美国人。当家长报告的PACCI方向从“较好”变为“较差”时，我们观察到哮喘控制较差（P< 0.001），儿童哮喘护理人员生活质量问卷（PACQLQ）平均得分（P< 0.001）和FEV1% （P= 0.025）。线性回归显示，PACCI方向每改变一次，PACQLQ平均评分下降- 0.6 （95% CI, - 0.8 ~ - 0.4）。当家长报告的PACCI困扰从“不困扰”变为“非常困扰”时，我们观察到哮喘控制较差（P< 0.001），平均PACQLQ评分较低（P< 0.001）。线性回归显示，每改变一次PACCI Bother类别，平均PACQLQ评分下降- 1.1 （95% CI, - 1.3至- 0.9）。任何报告的PACCI风险事件（急诊科就诊、住院或使用口服皮质类固醇）与较差的哮喘控制（P< 0.05）和PACQLQ评分（P< 0.01）相关。结论spacci Direction、Bother和Risk是衡量家长报告结果的有效指标，具有良好的判别效度。PACCI是一种简单的临床工具，用于评估家长报告的哮喘发病率的多个维度，以及风险和控制。
BackgroundDespite a growing interest, few pediatric asthma questionnaires assess multiple dimensions of asthma morbidity, as recommended by national asthma guidelines, or use patient-reported outcomes.ObjectiveTo evaluate a questionnaire that measures multiple dimensions of parent-reported asthma morbidity (Direction, Bother, and Risk).MethodsWe administered the Pediatric Asthma Control and Communication Instrument (PACCI) and assessed asthma control (PACCI Control), quality of life, and lung function among children who presented for routine asthma care. The PACCI was evaluated for discriminative validity.ResultsA total of 317 children participated (mean age, 8.2 years; 58% boys; 44% African American). As parent-reported PACCI Direction changed from “better” to “worse,” we observed poorer asthma control (P< .001), mean Pediatric Asthma Caregiver Quality of Life Questionnaire (PACQLQ) scores (P< .001), and FEV1% (P= .025). Linear regression showed that, for each change in PACCI Direction, the mean PACQLQ score decreased by −0.6 (95% CI, −0.8 to −0.4). As parent-reported PACCI Bother changed from “not bothered” to “very bothered,” we observed poorer asthma control (P< .001) and lower mean PACQLQ scores (P< .001). Linear regression showed that, for each change in PACCI Bother category, the mean PACQLQ score decreased by −1.1 (95% CI, −1.3 to −0.9). Any reported PACCI Risk event (emergency department visit, hospitalization, or use of an oral corticosteroid) was associated with poorer asthma control (P< .05) and PACQLQ scores (P< .01).ConclusionsPACCI Direction, Bother, and Risk are valid measures of parent-reported outcomes and show good discriminative validity. The PACCI is a simple clinical tool to assess multiple dimensions of parent-reported asthma morbidity, in addition to risk and control.