A Clinicopathologic Analysis of 207 Cases of Benign Fibro-Osseous Lesions of the Jaws
A Clinicopathologic Analysis of 207 Cases of Benign Fibro-Osseous Lesions of the Jaws
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DOI：
10.1177/1066896913511985
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发表时间：
2014-06-01
影响因子：
1.2
通讯作者：
Tiranon, Prawwalee
中科院分区：
文献类型：
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作者：
Phattarataratip, Ekarat;Pholjaroen, Chanajit;Tiranon, Prawwalee
良性纤维骨病变（BFOL）是一组独特的颌骨实体，由纤维细胞组织和矿化材料组成。在这项研究中，我们检查了 BFOL 患者的流行病学、临床和病理特征。对提交给病理学服务的 207 例 BFOL 的记录和显微载玻片进行了回顾性审查。总体而言，纤维发育不良（FD）最常见（36.7%），其次是骨化纤维瘤（OF；32.4%）、骨发育不良（OD；24.6%）和幼年骨化纤维瘤（JOF；6.3%）。注意到女性的偏好。 FD和JOF常见于上颌骨，而OF和OD大多数影响下颌骨。大多数 FD 和 OF 患者表现为无痛肿胀，而 OD 患者则无症状。大多数 FD 标本显示编织骨，而 OF 和 OD 中经常注意到编织骨和牙骨质样材料的混合物。我们的数据显示 BFOL 的临床病理特征存在差异。对 BFOL 患者的各个方面进行彻底检查对于准确诊断至关重要。
Benign fibro-osseous lesion (BFOL) is a distinct group of jaw entities composed of fibrocellular tissue and mineralized materials. In this study, we examined the epidemiological, clinical, and pathological features of patients with BFOL. Records and microslides of 207 BFOLs submitted to pathology service were retrospectively reviewed. Overall, fibrous dysplasia (FD) was the most prevalent (36.7%), followed by ossifying fibroma (OF; 32.4%), osseous dysplasia (OD; 24.6%), and juvenile ossifying fibroma (JOF; 6.3%). Female predilection was noted. FD and JOF were common in maxilla, whereas most OF and OD affected the mandible. Most patients with FD and OF presented with painless swelling, while patients with OD were symptomless. The majority of FD specimens showed woven bone, while a mixture of woven bone and cementum-like materials was often noted in OF and OD. Our data show variations in the clinicopathologic features of BFOLs. A thorough examination of all aspects of BFOL patients is imperative for accurate diagnosis.