Stress, stress reduction and hypercholesterolemia in African Americans: a review.
Stress, stress reduction and hypercholesterolemia in African Americans: a review.
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发表时间：
1999
影响因子：
3.2
通讯作者：
R. Calderón;R. H. Schneider;C. N. Alexander;H. Myers;S. Nidich;C. Haney
中科院分区：
文献类型：
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作者：
R. Calderón;R. H. Schneider;C. N. Alexander;H. Myers;S. Nidich;C. Haney
心理压力可能直接导致非裔美国人冠心病发病率和死亡率及其病因危险因素过高。具体而言，急性和慢性应激已被证明会导致血清脂质升高，并与临床冠状动脉事件相关。压力导致脂质水平改变的机制尚不完全清楚，但已经涉及多种途径（即激素、饮食等）。降低血清脂质的传统方法包括饮食、药物或两者兼而有之。这些方法因合规性、副作用和成本问题而受到批评。由于这些局限性，国家胆固醇教育计划推荐非药物行为方法作为预防和治疗高胆固醇血症和其他危险因素的一线方法。研究表明，冠心病的发病率和死亡率以及主要危险因素可以通过行为干预来改变。具体来说，先验冥想技术是一种有效的压力解毒剂，可以降低主要冠心病危险因素的水平，包括高胆固醇血症、血压和吸烟。对于非洲裔美国人来说，使用有效的减压方法来预防和治疗先心病及其危险因素可能会成为这一服务不足的人群的宝贵财富。
Psychological stress may directly contribute to the disproportionately high rates of coronary heart disease morbidity and mortality and its etiologic risk factors in African Americans. Specifically, acute and chronic stress have been shown to raise serum lipids and are associated with clinical coronary events. The mechanisms by which stress contributes to alterations in lipid levels are not fully known, but various pathways (ie, hormonal, dietary, etc) have been implicated. Traditional methods for reducing blood serum lipids include diet, drugs or both. These methods have been criticized because of issues of compliance, side effects, and cost. Because of these limitations, nondrug behavioral methods are recommended by the National Cholesterol Education Program as the first line of prevention and treatment for hypercholesterolemia and other risk factors. Research shows that CHD morbidity and mortality and major risk factors may be modifiable by behavioral intervention. Specifically, the Transcendental Meditation technique, an effective antidote to stress, reduces levels of major CHD risk factors including hypercholesterolemia, as well as blood pressure and smoking. Using an effective stress reduction approach for prevention and treatment of CHD and its risk factors in African Americans may prove to be a valuable asset for this underserved population.