Heart rate variability and hematological parameters in pregnant women
Heart rate variability and hematological parameters in pregnant women
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DOI：
10.1002/jcla.23250
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发表时间：
2020-02-24
影响因子：
2.7
通讯作者：
Adam, Ishag
中科院分区：
文献类型：
--
作者：
Al-Shafei, Ahmad I.;Musa, Shaza M.;Adam, Ishag
背景目前对血液学指标（血红蛋白、红细胞分布宽度（RDW）、白色细胞（WBC）、平均血小板体积（MPV）、心率变异性（HRV））的研究较少。有没有发表的数据在这个概念（心率变异性和血液学参数）在pregnancy.Methods的横断面研究进行了在萨阿德阿布埃拉医院在喀土穆，苏丹在2018年7月至8月期间。本研究入组了单胎（活胎）妊娠女性。进行病史和检查。采用时域和频域心率变异性指标对105例孕妇的心率自主调节进行评估。年龄、产次和胎龄的中位数（四分位数）分别为30.0（25.0-35.0）岁、1.0（0-3.0）周和38.0（32.0-39.0）周。血红蛋白与低频（LF）、RDW与高频（HF）、WBC与HF Norm、WBC与LF/HF、MPV与HF Norm、LF Norm与LF/HF呈正相关，而血液学指标（血红蛋白、WBC、RDW、MPV）与HRV无显著相关性。线性回归分析显示年龄、产次、胎龄、体重指数、血红蛋白、RDW和HRV变量之间无显著相关性。Log（10）WBC与Log（10）HF（ms（2）/Hz）呈负相关。MPV与LF Norm呈正相关，与HF Norm呈负相关。结论年龄、产次、胎龄、血红蛋白、RDW与HRV变量之间无显著相关性。WBC与HF呈负相关。MPV与LF Norm呈正相关，与HF Norm呈负相关。
Background There are few researches on hematological parameters (hemoglobin, red cell distribution width [RDW], white blood cells [WBCs], mean platelets volume [MPV], and heart rate variability [HRV]). There are no published data on this concept (HRV and hematological parameters) during pregnancy.Methods A cross-sectional study was conducted at Saad Abul Ela hospital in Khartoum, Sudan during the period of July to August 2018. Pregnant women with singleton, a live baby, were enrolled in this study. Clinical history and examination were performed. HRV (autonomic modulation) was assessed using time and frequency domain HRV indices.Results One hundred and five pregnant women were enrolled. The median (quartile) of the age, parity, and gestational age was 30.0 (25.0-35.0) years, 1.0 (0-3.0), and 38.0 (32.0-39.0) weeks, respectively. While there were positive correlations between hemoglobin and low frequency (LF), RDW and high frequency (HF), WBCs and HF Norm, WBCs and LF/HF, MPV and HF Norm, LF Norm and LF/HF, there was no significant correlation between the hematological (hemoglobin, WBCs, RDW, and MPV) and HRV parameters. Linear regression analysis showed no significant association between age, parity, gestational age, body mass index, hemoglobin, RDW, and HRV variables. The Log(10) WBCs were negatively associated with Log(10) HF (ms(2)/Hz). MPV was positively associated with LF Norm and negatively associated with HF Norm.Conclusion The study failed to show significant associations between age, parity, gestational age, hemoglobin, RDW, and HRV variables. The WBCs were negatively associated with HF. MPV was positively associated with LF Norm, and it was negatively associated with HF Norm.