A Case of Pediatric Alcohol-Associated Hepatitis Evaluated for Liver Transplant Listing.
A Case of Pediatric Alcohol-Associated Hepatitis Evaluated for Liver Transplant Listing.
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DOI：
10.1097/pg9.0000000000000311
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发表时间：
2023-05
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酒精相关性肝炎（AH）是指酒精摄入引起的肝损伤，通常发生在多年重度酒精滥用后。经常大量饮酒会导致肝脏炎症、纤维化和肝硬化。一些患者发展为严重的AH，其具有较高的短期死亡率，并且是全球成人肝移植（LT）的第二常见原因。我们提出了第一个案件的青少年诊断为严重AH，导致LT评估之一。我们的病人是一个15岁的男性谁提出了鼻出血和1个月的黄疸后，3年的日常酗酒。我们与成人移植肝脏科医生同事合作，启动了一项管理计划，其中包括治疗急性酒精戒断、类固醇使用、心理健康支持和LT评估。
Alcohol-associated hepatitis (AH) refers to liver injury from alcoholic intake that usually occurs after years of heavy alcohol abuse. Frequent, heavy alcohol consumption causes hepatic inflammation, fibrosis, and cirrhosis. Some patients develop severe AH, which carries high short-term mortality and is the second most common reason for adult liver transplants (LTs) worldwide. We present one of the first cases of a teenager diagnosed with severe AH that led to LT evaluation. Our patient was a 15-year-old male who presented with epistaxis and 1 month of jaundice after 3 years of heavy daily alcohol abuse. In collaboration with our adult transplant hepatologist colleagues, we initiated a management plan that consisted of treating acute alcohol withdrawal, steroid utilization, mental health support, and LT evaluation.