MRC-SPECT: A sub-500 μm resolution MR-compatible SPECT system for simultaneous dual-modality study of small animals.
MRC-SPECT: A sub-500 μm resolution MR-compatible SPECT system for simultaneous dual-modality study of small animals.
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DOI：
10.1016/j.nima.2013.08.080
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发表时间：
2014-01-11
期刊：
影响因子：
--
通讯作者：
Meng LJ
中科院分区：
文献类型：
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作者：
Cai L;Lai X;Shen Z;Chen CT;Meng LJ
在本文中，我们将报告一个高分辨率MR兼容的SPECT系统，可以在一个预先存在的临床MR扫描仪同时双模态成像的小动物的发展。该系统是由40个小像素的碲化镉探测器模块组装在一个完全固定的环SPECT几何。我们已经通过实验证明，当在MR扫描仪内操作时，该系统能够提供<500 μm的成像分辨率。我们将报告MRI兼容SPECT系统的设计、构建，包括探测器技术、准直器、系统开发等，并将报告使用这种新构建的SPECT系统获得的第一批成像结果。
In this paper, we will report the development of an ultrahigh resolution MR-compatible SPECT system that can be operated inside a pre-existing clinical MR scanner for simultaneous dual-modality imaging of small animals. This system is constructed with 40 small-pixel CdTe detector modules assembled in a fully stationary ring SPECT geometry. We have experimentally demonstrated that this system is capable of providing an imaging resolution of <500 μm when operating inside MR scanners. We will report the design, construction of the MRI-compatible SPECT system, including the detector technology, collimator, system development and so on. The first imaging results obtained with this newly constructed SPECT system will also be reported.