Tandem Hydroformylation–Biginelli Reaction
Tandem Hydroformylation–Biginelli Reaction
复制标题
串联氢甲酰化-Biginelli 反应
作者：
D. Fuchs;M. Nasr-Esfahani;L. Diab;T. Smejkal;B. Breit
串联法与多组分反应相结合是高原子经济性合成的新途径。建立了串联氢甲酰化- biginelli反应序列，得到了多种功能化的4-烷基取代3,4-二氢嘧啶-2(1H)- 1。
The combination of a tandem process with a multicomponent reaction is a new approach to high atom-economic synthesis. A tandem hydroformylation–Biginelli reaction sequence has been developed leading to a variety of functionalized 4-alkyl-substituted 3,4-dihydropyrimidin-2(1H)-ones.