Measures of and tests for net improvement in clinical trials, PhD.
Measures of and tests for net improvement in clinical trials, PhD.
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临床试验净改善的测量和测试，博士。
DOI：
10.1016/0197-2456(88)90003-7
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Kimball,AW
中科院分区：
文献类型：
--
作者：
Kimball,AW
For clinical trials in which the outcome variable is trichotomous (regression, no change, improvement), a measure of net improvement in health status is proposed. Test statistics are derived for the null hypothesis of zero net improvement in a single patient group and for the null hypothesis of no difference in net improvement between two groups. The methods are applied to a clinical trial that evaluated the effect of argon laser photocoagulation in patients with macular edema in branch vein occlusion.
