Coordinated diameter oscillations at arteriolar bifurcations in skeletal muscle.
Coordinated diameter oscillations at arteriolar bifurcations in skeletal muscle.
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骨骼肌小动脉分叉处的协调直径振荡。
DOI：
10.1152/ajpheart.1987.253.3.h568
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Intaglietta,M
中科院分区：
文献类型：
--
作者：
Meyer,JU;Lindbom,L;Intaglietta,M
用显微视频光度系统观察了家兔极薄肌微血管分叉处的自发性节律性管腔变化（血管运动）。视频场景，包含两个终端小动脉起源于一个横向小动脉，显示相邻的终端小动脉收缩同步在26 31收缩周期。在75%的周期中，60个载瘤横血管收缩的发生与终末小动脉的活动同步，25%的周期延迟。横支血管运动明显小于终末血管。不同动物的所有终末小动脉以18.9 +/- 3.5周期/分钟的基频振荡。我们得出结论，在骨骼肌微循环中，1）协调的自发直径振荡发生在邻近的小动脉中，2）直径变化在终末小动脉中最明显，3）协调的血管运动在该组织中表现出特征性的窄带频率。假设存在微血管起搏器。
The spontaneous rhythmical luminal changes (vasomotion) at bifurcations in the microvasculature of the rabbit tenuissimus muscle were investigated by means of a microscope video photometric system. Video scenes, containing two terminal arterioles originating from one transverse arteriole, showed that adjacent terminal arterioles constricted synchronously in 26 out of 31 contraction cycles. The onset of 60 constrictions in the parent transverse vessels was synchronized with the activity in terminal arterioles in 75% of the cycles and delayed in 25%. Vasomotion in the parent transverse vessels was notably smaller than in the terminal vessels. All the terminal arterioles in the different animals oscillated at the fundamental frequency of 18.9 +/- 3.5 cycles/min. We conclude that in the skeletal muscle microcirculation 1) coordinated spontaneous diameter oscillations occur in arterioles that are in proximity, 2) diameter changes are most pronounced in the terminal arterioles, and 3) coordinated vasomotion in this tissue exhibits a characteristic narrow band frequency. The presence of a microvascular pacemaker is hypothesized.