Developmental and evolutionary significance of the mandibular arch and prechordal/premandibular cranium in vertebrates: revising the heterotopy scenario of gnathostome jaw evolution
Developmental and evolutionary significance of the mandibular arch and prechordal/premandibular cranium in vertebrates: revising the heterotopy scenario of gnathostome jaw evolution
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DOI：
10.1111/j.1469-7580.2012.01505.x
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发表时间：
2013-01
影响因子：
2.4
通讯作者：
S. Kuratani;N. Adachi;N. Wada;Yasuhiro Oisi;F. Sugahara
中科院分区：
文献类型：
--
作者：
S. Kuratani;N. Adachi;N. Wada;Yasuhiro Oisi;F. Sugahara
头神经脊产生大量的迁移细胞，这些细胞分布在咽弓和更靠嘴的颌前区，从而在胚胎脊椎动物的头部形成广泛的外胚间充质。形成三叉神经流的嵴细胞是颅面骨骼的主要来源；然而，在这个外胚间充质中，下颌弓和下颌前区之间没有明显的区别。关于颌骨的进化的问题，部分是关于下颌弓的分化的问题，也是关于咽部的喙的组成部分的问题，部分是关于下颌前域的发育命运的问题。我们讨论了下颌弓的发育定义与小梁的发育起源、通常认为在下颌前区域发育的成对软骨元素以及称为极地软骨的神秘软骨元素。在比较胚胎学的基础上，我们认为下颌口内的下颌弓外胚间充质可以被定义为Dlx1阳性的结构域，而由Dlx1阴性的下颌前外胚间充质发育而来的极地软骨仅代表小梁的后部。我们还显示，在七鳃鳗胚胎中，下颌弓间充质早期迁移到下颌前域，并提出了关于颌骨起源的异位理论的更新版本。
The cephalic neural crest produces streams of migrating cells that populate pharyngeal arches and a more rostral, premandibular domain, to give rise to an extensive ectomesenchyme in the embryonic vertebrate head. The crest cells forming the trigeminal stream are the major source of the craniofacial skeleton; however, there is no clear distinction between the mandibular arch and the premandibular domain in this ectomesenchyme. The question regarding the evolution of the gnathostome jaw is, in part, a question about the differentiation of the mandibular arch, the rostralmost component of the pharynx, and in part a question about the developmental fate of the premandibular domain. We address the developmental definition of the mandibular arch in connection with the developmental origin of the trabeculae, paired cartilaginous elements generally believed to develop in the premandibular domain, and also of enigmatic cartilaginous elements called polar cartilages. Based on comparative embryology, we propose that the mandibular arch ectomesenchyme in gnathostomes can be defined as a Dlx1‐positive domain, and that the polar cartilages, which develop from the Dlx1‐negative premandibular ectomesenchyme, would represent merely posterior parts of the trabeculae. We also show, in the lamprey embryo, early migration of mandibular arch mesenchyme into the premandibular domain, and propose an updated version of the heterotopy theory on the origin of the jaw.