Predictors of recurrent febrile seizures - A prospective cohort study
Predictors of recurrent febrile seizures - A prospective cohort study
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DOI：
10.1001/archpedi.1997.02170410045006
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发表时间：
1997-04-01
影响因子：
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通讯作者：
Hauser, AW
中科院分区：
文献类型：
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作者：
Berg, AT;Shinnar, S;Hauser, AW
目的：确定单次和多次反复发热性惊厥的风险和预测因素。方法：对428例首次出现发热性惊厥的儿童进行前瞻性识别并随访2年以上。父母在他们的孩子第一次热性惊厥后很快被访问，每3个月被访问一次以确定反复的热性惊厥。审查了首次和反复发作的医疗记录，以获取更多信息。结果：136例患儿（31.8%）有癫痫复发，其中1次复发73例（17.1%），2次复发38例（8.9%），3次及以上25例（5.8%）。起病年龄小、一级亲属有热性惊厥史、在急诊科时低热、起病与初次惊厥之间时间短是反复热性惊厥的有力独立预测因素。将这4个因素结合起来，就有可能定义复发概率非常高和非常低的儿童群体(70% vs 60% vs
Objectives: To define the risk and identify predictors of single and multiple recurrent febrile seizures.Methods: Children (n=428) with first febrile seizures were prospectively identified and followed for 2 or more years. Parents were interviewed soon after their children's first febrile seizure and were called every 3 months to ascertain recurrent febrile seizures. Medical records of first and recurrent seizures were reviewed for additional information.Results: A total of 136 children (31.8%) experienced recurrent seizures: 73 (17.1%) had only 1 recurrence, 38 (8.9%) had 2 recurrences, and 25 (5.8%) had 3 or more recurrences. Young age at onset, a history of febrile seizures in a first-degree relative, low degree of fever while in the emergency department, and a brief duration between the onset of fever and the initial seizure were strong independent predictors of recurrent febrile seizures. With these 4 factors combined, it is possible to define groups of children having very high and very low probabilities of having any recurrences (>70% vs 60% vs