A rare case of metastases to the maxillary sinus from sigmoid colon adenocarcinoma
A rare case of metastases to the maxillary sinus from sigmoid colon adenocarcinoma
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DOI：
10.1159/000066076
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发表时间：
2002-09-01
期刊：
影响因子：
--
通讯作者：
Scarano, E
中科院分区：
文献类型：
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作者：
Cama, E;Agostino, S;Scarano, E
恶性肿瘤转移到鼻腔和鼻窦是罕见的。回顾世界文献报道，只有4例胃窦转移从胃肠道癌。我们报告一个乙状结肠狭窄性腺癌转移至上颌窦的病例。耳鼻喉科体检发现肿块累及右侧牙槽嵴和右侧硬腭。头部及颈部CT示一不规则肿物，累及右侧上颌窦、颞下窝及翼状肌，右侧牙槽嵴后段及右侧上颌窦后壁骨吸收。肿瘤组织CEA及细胞角蛋白20表达明显阳性，证实结直肠腺癌转移至上颌窦。当必须对上颌窦第二原发肿瘤和转移瘤进行鉴别诊断时，应考虑胃肠道，并进行详细的免疫组织化学检查。版权所有(C) 2002 S. Karger AG，巴塞尔。
Metastases of malignant tumors to the nasal cavity and paranasal sinuses are rare. A review of the world's literature reports only four cases of antral metastases from carcinoma of gastrointestinal tract. We present a case of a stenosing adenocarcinoma of the sigmoid colon with metastases within the maxillary sinus. The ENT physical examination revealed a mass involving the right alveolar ridge, the right hard palate. CT scan of the head and the neck showed a large and irregular mass involving the right maxillary sinus, the infratemporal fossa and the pterygoid muscles with resorption of the bone of the posterior portion of the right alveolar ridge and of the posterior wall of the right maxillary sinus. The neoplastic tissue showed marked positivity for CEA and expressed cytokeratin 20, confirming the diagnosis of metastases to the maxillary sinus from colorectal adenocarcinoma. When a differential diagnosis between a second primary tumor of the maxillary sinus and a metastasis has to be carried out, the gastrointestinal tract should be taken into account and detailed immunohistochemical should be performed. Copyright (C) 2002 S. Karger AG, Basel.