The [4+2] cycloaddition of donor-acceptor cyclobutanes and nitrosoarenes.
The [4+2] cycloaddition of donor-acceptor cyclobutanes and nitrosoarenes.
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DOI：
10.1039/c3cc47775d
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发表时间：
2014-01
影响因子：
4.9
通讯作者：
Naresh Vemula;Andrew C. Stevens;Tyler B. Schon;B. Pagenkopf
中科院分区：
文献类型：
--
作者：
Naresh Vemula;Andrew C. Stevens;Tyler B. Schon;B. Pagenkopf
公开了Yb(OTf)3催化的给体-受体环丁烷和亚硝基芳烃之间的[4+2]环加成反应。这种方法有利于以良好到优异的产率合成四氢-1，2-恶嗪作为单一非对映异构体。除了少数缺乏电子的亚硝基芳烃外，在整个研究过程中都观察到了良好的区域选择性。
The Yb(OTf)3 catalyzed [4+2] cycloaddition between donor-acceptor cyclobutanes and nitrosoarenes is disclosed. This method facilitates the synthesis of tetrahydro-1,2-oxazines in good to excellent yields as single diastereomers. Except for a few electron-deficient nitrosoarenes, excellent regioselectivity was observed throughout these studies.