Lifetime risk of stroke and impact of hypertension: estimates from the adult health study in Hiroshima and Nagasaki
Lifetime risk of stroke and impact of hypertension: estimates from the adult health study in Hiroshima and Nagasaki
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DOI：
10.1038/hr.2011.7
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发表时间：
2011-05-01
影响因子：
5.4
通讯作者：
Matsumoto, Masayasu
中科院分区：
文献类型：
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作者：
Takahashi, Ikuno;Geyer, Susan M.;Matsumoto, Masayasu
很少有关于血压（BP）组卒中终身风险（LTR）的报告。这项研究包括参加辐射影响研究基金会成人健康研究的人，他们自1958年以来每两年进行一次健康检查。我们计算了7847名在55岁之前未被诊断为卒中的受试者中不同BP组的卒中LTR，使用累积发病率分析调整了竞争风险。到2003年，868名受试者患有中风（512名（58.9%）为女性，542名（62.4%）患有缺血性中风）。血压是决定男性和女性中风风险的重要因素，不同血压组的中风累积风险分布有显著差异。在45岁、55岁、65岁和75岁的任何指数年龄，正常血压（收缩压/舒张压160/100 mm Hg）的所有卒中的LTR在男性中分别为13.8-16.9-25.8-25.8%，在女性中分别为16.0-19.9-24.0-30.5%（P140/90 mm Hg）。高血压研究（2011）34，649-654; doi：10.1038/hr.2011.7;在线发布2011年2月17日
Very few reports have been published on lifetime risk (LTR) of stroke by blood pressure (BP) group. This study included participants in the Radiation Effects Research Foundation Adult Health Study who have been followed up by biennial health examinations since 1958. We calculated the LTR of stroke for various BP-based groups among 7847 subjects who had not been diagnosed with stroke before the index age of 55 years using cumulative incidence analysis adjusting for competing risks. By 2003, 868 subjects had suffered stroke (512 (58.9%) were women and 542 (62.4%) experienced ischemic stroke). BP was a significant factor in determining risk of stroke for men and women, with distributions of cumulative risk for stroke significantly different across BP groups. The LTR of all-stroke for normotension (systolic BP/diastolic BP 160/100 mm Hg) were 13.8-16.9-25.8-25.8% in men and 16.0-19.9-24.0-30.5% in women, respectively (P140/90 mm Hg) at any of the index ages of 45, 55, 65 and 75 years. Hypertension Research (2011) 34, 649-654; doi:10.1038/hr.2011.7; published online 17 February 2011