The anatomy of the cardiac veins in mice
The anatomy of the cardiac veins in mice
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DOI：
10.1111/j.1469-7580.2007.00753.x
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发表时间：
2007-07-01
影响因子：
2.4
通讯作者：
Ratajska, Anna
中科院分区：
文献类型：
--
作者：
Ciszek, Bogdan;Skubiszewska, Daria;Ratajska, Anna
虽然许多研究实验室已经详细研究了小鼠的心脏冠状动脉系统，但对心脏静脉的了解仍然很少。这是因为难以用一种技术标记静脉系统，这种技术可以使这些薄壁的大血管可视化。在这里，我们提出了通过右尾静脉灌注乳胶染料的冠状静脉系统的可视化。静脉注射的乳胶不会渗透到毛细血管系统。小鼠心脏静脉由几个主要分支（直径较大）组成，其远端部分位于心外膜下。我们已经描述了左心房静脉、左心室静脉、尾静脉、右心室静脉和圆锥静脉的主要分支，这些静脉形成圆锥静脉环或肺前圆锥静脉弓，环绕右心室圆锥。心脏的静脉系统将血液引流到冠状窦（左颅腔静脉）、右心房或右颅腔静脉。体静脉如左颅腔静脉、右颅腔静脉和尾静脉通向右心房。心脏静脉位置的知识可能有助于阐明某些遗传畸形的异常静脉模式。
Although the cardiac coronary system in mice has been the studied in detail by many research laboratories, knowledge of the cardiac veins remains poor. This is because of the difficulty in marking the venous system with a technique that would allow visualization of these large vessels with thin walls. Here we present the visualization of the coronary venous system by perfusion of latex dye through the right caudal vein. Latex injected intravenously does not penetrate into the capillary system. Murine cardiac veins consist of several principal branches (with large diameters), the distal parts of which are located in the subepicardium. We have described the major branches of the left atrial veins, the vein of the left ventricle, the caudal veins, the vein of the right ventricle and the conal veins forming the conal venous circle or the prepulmonary conal venous arch running around the conus of the right ventricle. The venous system of the heart drains the blood to the coronary sinus (the left cranial caval vein) to the right atrium or to the right cranial caval vein. Systemic veins such as the left cranial caval, the right cranial caval and the caudal vein open to the right atrium. Knowledge of cardiac vein location may help to elucidate abnormal vein patterns in certain genetic malformations.