VARIABILITY OF THE TERRITORIES OF THE MAJOR CEREBRAL-ARTERIES
VARIABILITY OF THE TERRITORIES OF THE MAJOR CEREBRAL-ARTERIES
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DOI：
10.3171/jns.1992.77.6.0927
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发表时间：
1992-12-01
影响因子：
4.1
通讯作者：
DRAGOVIC, L
中科院分区：
文献类型：
--
作者：
VANDERZWAN, A;HILLEN, B;DRAGOVIC, L
最近对威利斯圈的形态学和功能研究表明，与普遍接受的相对一致的模式相反，大脑六大动脉的供应区域在分布上表现出相当大的变化；因此，在常规尸检中获得的25个未固定的人脑中，研究了这些动脉区域的皮层和脑内分布。在标准条件下，在相同压力下同时注射不同颜色的Araldite F混合物，以获得最真实的区域分布。检查并记录脑回和脑沟的皮质边界，分析和比较大脑前、中、后动脉的区域。在将注射的大脑切成平行切片后，研究了这些区域的脑内分布。这些动脉区域的可变性比文献中一般描述的要大得多。在50个大脑半球的皮层中，发现大脑前动脉区域有26个变异，大脑中动脉区域有17个变异，大脑后动脉区域有22个变异。脑内，大脑前、中、后动脉在不同程度上为脑叶白质、内囊、尾状核和状核的血液供应做出了贡献。这些区域之间的皮层和脑内边界所处区域的巨大差异通过说明每个区域的最小和最大范围来证明。结果与先前的研究结果进行了比较，并讨论了它们对实验模型研究和临床实践的影响。
Recent morphological and functional studies on the circle of Willis suggest that the areas of supply of the six major cerebral arteries show a considerable variation in distribution, in contrast to the relatively consistent pattern generally accepted; therefore, the cortical and intracerebral distribution of the territories of these arteries was investigated in 25 unfixed human brains obtained at routine autopsy. The six major cerebral arteries were simultaneously injected under the same pressure with different-colored Araldite F mixtures under standardized conditions to obtain the most realistic territorial distribution. The cortical boundaries were examined and recorded in relation to the cerebral gyri and sulci, and the territories of the anterior, middle, and posterior cerebral arteries were analyzed and compared. The intracerebral distribution of these territories was investigated after the injected brains were cut in parallel slices. The variability of the territories of these arteries was much larger than generally described in the literature. Twenty-six variations in the territory of the anterior cerebral artery, 17 variations in the area of the middle cerebral artery, and 22 variations in the area of the posterior cerebral artery were found in the cortex of 50 hemispheres. Intracerebrally, the anterior, middle, and posterior cerebral arteries contributed in varying degrees to the blood supply of the lobar white matter, the internal capsule, the caudate nucleus, and the lentiform nucleus. The large variation in the area in which the cortical and intracerebral boundaries between these territories was located was demonstrated by illustrating the minimum and maximum extent of each. The results are compared with prior findings, and their implications for both experimental model studies and clinical practice are discussed.