Ecotoxicological Test Assay Using OECD TG 212 in Marine Java Medaka (Oryzias javanicus) and Freshwater Japanese Medaka (Oryzias latipes)
Ecotoxicological Test Assay Using OECD TG 212 in Marine Java Medaka (Oryzias javanicus) and Freshwater Japanese Medaka (Oryzias latipes)
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DOI：
10.1007/s00128-018-2398-1
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发表时间：
2018-09-01
影响因子：
2.7
通讯作者：
Tatarazako, Norihisa
中科院分区：
文献类型：
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作者：
Horie, Yoshifumi;Kanazawa, Nobuhiro;Tatarazako, Norihisa
化学品的致死效应是生态系统保护的一个严重问题，OECD TG 212是为了估计鱼类胚胎和囊鱼苗阶段的致死和亚致死效应而制定的。然而，目前还不清楚这种测试是否能有效地估计化学品对海洋鱼类的影响。因此，本研究的目的是使用公认的测试方法对海洋鱼类Oryzias javanicus，并评估有机锡化合物之间的反应的差异，淡水同源物（Oryzias latipes）和O。爪哇人。三苯基锡致死效应的最低观察效应浓度（LOEC）在两个物种中相同。三丁基锡对两种物种的致死和亚致死效应的最低可见效应浓度相同。我们的结果首次证明O. javanicus和O. latipes同样受到有机锡化合物的影响，这表明O. javanicus是化学品生态毒理学评估的良好模式海洋鱼类。
The lethal effects of chemicals is a serious concern to the protection of ecosystems, and the OECD TG 212 was established to estimate the lethal and sublethal effects on embryo and sac-fry stages of fish. It is still unclear, however, whether this test can effectively estimate the impacts of chemicals using marine fish. Therefore, this study aimed to use a recognized testing method on the marine fish Oryzias javanicus, and to assess differences in response to organotin compounds between a freshwater congener (Oryzias latipes) and O. javanicus. The lowest observed effect concentration (LOEC) of triphenyltin for lethal effect was the same in both species. The LOEC of tributyltin for lethal and sublethal effects were the same in both species. Our results provide the first evidence that O. javanicus and O. latipes are similarly affected by organotin compounds, suggesting that O. javanicus is a good model marine fish for the ecotoxicological assessment of chemicals.