Effects of Smoking on Central Corneal Thickness and the Corneal Endothelial Cell Layer in Otherwise Healthy Subjects
Effects of Smoking on Central Corneal Thickness and the Corneal Endothelial Cell Layer in Otherwise Healthy Subjects
复制标题
DOI：
10.1097/icl.0000000000000212
复制
发表时间：
2016-09-01
影响因子：
2.3
通讯作者：
Keskin, Ugurcan
中科院分区：
文献类型：
--
作者：
Ilhan, Nilufer;Ilhan, Ozgur;Keskin, Ugurcan
目的：吸烟对中央角膜厚度（CCT），角膜内皮细胞密度（ECD），和形态的影响进行了评估，否则healthy subjects.Methods：本研究包括103个当前吸烟者和106个健康的非吸烟者没有任何眼部疾病，除了屈光不正。内皮细胞密度，六边形的百分比，和变异系数（CV）的细胞大小的测定使用非接触式镜面显微镜。中央角膜厚度测量超声pachymetry.Results：在非吸烟者组的参与者的平均年龄为31.4 - 5.1岁（18-60）和33.0 +/- 9.1岁（18-58）在当前吸烟者组。非吸烟者组的平均CCT值为523.7 +/- 34 m，吸烟者组为518.5 +/- 37 m。非吸烟者组的平均ECD、CV和六边形百分比值分别为2，881 +/- 293.7个细胞/平方毫米、32.5 +/-6%和56.6 +/- 11%，吸烟者组分别为2，681 +/- 323.9个细胞/平方毫米、33.4 +/-5%和55.5 +/- 10%。尽管两组之间的CCT、CV和六边形值百分比没有差异，但ECD值有显著差异（P
Objectives:The effects of smoking on central corneal thickness (CCT), corneal endothelial cell density (ECD), and morphology were evaluated in otherwise healthy subjects.Methods:The study included 103 current smokers and 106 healthy nonsmoking subjects without any eye disease apart from refractive errors. Endothelial cell density, percentage of hexagonality, and coefficient of variation (CV) in cell size were measured using noncontact specular microscopy. Central corneal thickness was measured by ultrasound pachymetry.Results:The mean age of participants in the nonsmoker group was 31.4 5.1 years (18-60) and 33.0 +/- 9.1 years (18-58) in the current smoker group. The mean CCT value was 523.7 +/- 34 m in the nonsmoker group and 518.5 +/- 37 m in the smoker group. The mean ECD, CV, and percentage of hexagonality values were 2,881 +/- 293.7 cells per square millimeter, 32.5 +/- 6%, and 56.6 +/- 11% in the nonsmoker group, and 2,681 +/- 323.9 cells per square millimeter, 33.4 +/- 5%, and 55.5 +/- 10% in the smoker group, respectively. Although there was no difference between the groups in terms of CCT, CV, and percentage of hexagonality values, a significant difference was determined in the case of ECD values (P