ANALYSIS OF TRACE ELEMENTS IN PRE- AND POST-NATAL TOOTH ENAMEL USING MICRO-PIXE
ANALYSIS OF TRACE ELEMENTS IN PRE- AND POST-NATAL TOOTH ENAMEL USING MICRO-PIXE
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使用 Micro-PIXE 分析产前和产后牙釉质中的微量元素
DOI：
10.1142/s0129083512400232
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
K.Igari et. al.
中科院分区：
文献类型：
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作者：
S. Kajita;S. Takamura and N. Ohno;Kimikazu Sasa;K.Igari et. al.
自然脱落的乳牙可能是环境暴露的生物标志物。为了评估儿童的产前环境，我们尝试在元素图上呈现新生儿线，并使用micro-PIXE研究出生前后形成的牙釉质中的微量元素。一般来说，新生儿线在出生时有一些困难的孩子的牙齿中观察得更清楚。在这项研究中，五个乳牙从五个儿童发育障碍进行分析。7种微量元素（Na，Mg，Si，Cl，Fe，Zn和Sr）在所有5颗牙齿的釉质中检测到。该线被认为是新生儿线，在牙齿中的Ca和P元素图上观察到严重的出生并发症的儿童。为了比较出生前后牙釉质中元素的浓度，将元素的浓度变化沿着垂直于新生儿线的线投影。出生前牙釉质中钙浓度较低。通过在其他元素图上追踪新生儿线的位置，以同样的方式比较所检测的微量元素的浓度。这些微量元素的含量在出生前后的牙釉质中差异不明显，统计学上有很大的差异。我们可以确定患有严重分娩并发症的孩子的牙釉质中新生儿线周围的微量元素分布和浓度。
Naturally shed deciduous teeth are potentially useful as a biomarker of environmental exposure. To assess the prenatal environment of child, we tried to present the neonatal line on the elemental maps and investigate the trace elements in pre- and post-natally formed tooth enamel using micro-PIXE. Generally, the neonatal line is observed more clearly in the tooth from child who has some difficulties at birth. In this study, five deciduous teeth from five children with developmental disorders were used for analysis. Seven trace elements (Na, Mg, Si, Cl, Fe, Zn, and Sr) were detected in enamel of all five teeth. The line, it was thought neonatal line, was observed on the elemental map of Ca and P in the tooth from the child with serious birth complications. In order to compare the elemental concentration between pre- and post-natal enamel, concentration variation of elements were projected along the line perpendicular to the neonatal line. Lower Ca concentration in prenatal enamel was observed. By tracing the location of neonatal line on the other elemental maps, the concentrations of detected trace elements were compared in the same way. The differences of concentration of these trace elements between pre- and post-natal enamel were not clear because of much statistic variation. We could determine the trace elemental profiles and concentrations around the neonatal line in the enamel from the child with serious birth complications.