Benzophenone and Padimate-O Protect Saccharomyces cerevisiae From UV Radiation and Cause Little Harm From UV-Induced Reactive Chemical Species
Benzophenone and Padimate-O Protect Saccharomyces cerevisiae From UV Radiation and Cause Little Harm From UV-Induced Reactive Chemical Species
复制标题
二苯甲酮和 Padimate-O 可保护酿酒酵母免受紫外线辐射，并且对紫外线引起的反应性化学物质造成的危害很小
DOI：
--
复制
发表时间：
2004
期刊：
影响因子：
--
通讯作者：
K. Zimmerman
中科院分区：
文献类型：
--
作者：
A. Beckett;B. McClure;K. Zimmerman
已经表明，防晒霜中使用的一些化合物在暴露于UV辐射时形成有害的反应性物质，这可能抵消防晒霜可能提供的保护益处。在紫外线存活试验期间，两种防晒化学品padimate-O和二苯甲酮为酿酒酵母提供的保护超过了化学品可能产生的潜在负面影响。对S无影响。当使酵母经受暴露于UVA光的化学品时，观察到酵母中的自由基，这表明该实验中的参数不足以在这些化学品中产生自由基，或者不能将化学品维持在激发态足够长的时间以对细胞产生任何影响。此外，细胞内自由基产生对酵母细胞的影响是最小的，并被直接紫外线辐射引起的细胞死亡所掩盖。
It has been shown that some of the compounds used in sunscreens form harmful reactive species upon exposure to UV radiation, which may counteract protective benefits the sunscreen may provide. The protection provided for Saccharomyces cerevisiae by two sunscreen chemicals, padimate-O and benzophenone, during a UV light survival assay outweighed potential negative effects that the chemicals may have had. No effect on S. cerevisiae was observed when the yeast were subjected to chemicals exposed to UVA light, suggesting that the parameters in this experiment were insufficient to generate free radicals in these chemicals, or were unable to maintain the chemicals in an excited state long enough to produce any effect on cells. Further, the effects of intracellular free radical generation on the yeast cells were minimal and were obscured by cell death caused by direct UV radiation.