Measurement of the spatial redistribution of water in rabbit achilles tendon in response to static tensile loading
Measurement of the spatial redistribution of water in rabbit achilles tendon in response to static tensile loading
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DOI：
10.1115/1.1800573
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发表时间：
2004-10-01
影响因子：
1.7
通讯作者：
Sotak, CH
中科院分区：
文献类型：
--
作者：
Helmer, KG;Wellen, J;Sotak, CH
在体外研究了兔跟腱对静态拉伸载荷的响应中水的重新分布。使用根据扩散加权磁共振 (MR) 数据拟合创建的一维质子密度图，沿径向线测量水的分布。在施加 5N (N=7) 和 10N (N=6) 拉伸载荷期间测量水的运动。在加载前和加载后 42 分钟内测量沿线的水分布。 5 或 10N 载荷的静态载荷导致肌腱外缘（边缘）的质子密度稳定增加。 10N 的负载降低了肌腱核心的质子密度，但在施加负载时观察到的一步是这样的。 5N 负载不会导致核心区域的质子密度发生变化。对于 10N 负载，从核心的立即重新分配具有统计显着性，但对于 5N 负载应用则不显着。无论负载条件如何，在加载后 42 分钟后，所有肌腱的边缘均观察到组内质子密度显着增加。边缘区域的质子密度、后负载增加的速率不取决于负载。 5N 负载情况下的速率为 0.010+/-0.00.2 min(-1)，10N 情况下的速率为 0.007+/-0.002 min(-1)。因此，虽然总体上与挤压模型一致，但数据显示了支持更复杂模型的其他特征。
The redistribution of water in response to static tensile loading was investigated in rabbit Achilles tendons in vitro. The distribution of water was measured along a radially oriented line, using a one-dimensional proton-density map created from fits to diffusion-weighted magnetic resonance (MR) data. Water movements were measured during application of tensile loads of 5N (N=7) and 10N (N=6). Water distribution along the line was measured before loading and up to 42 min after load application. Static loading with either 5 or 10N loads caused a steady increase in proton density in the outside edge (rim) of the tendon. The 10N load lowered the proton density in the core of the tendon, but did so in a single step that was observed when the load was applied. The 5N load caused no change in proton density in the core region. The immediate redistribution from the core was statistically significant for the 10N load, but not the 5N load application. Statistically significant within-group proton-density, increases were observed in the rim after 42 min postloadfor all tendons irrespective of load condition. The rate of proton-density, postload increase at the rim region did not depend upon load. The rate for the 5N load case was 0.010+/-0.00.2 min(-1) and 0.007+/-0.002 min(-1) in the 10N case. Thus, while generally consistent with an extrusion model, the data show other features that argue for a more complex model.