Schistosomes: surface, egg and circulating antigens.
Schistosomes: surface, egg and circulating antigens.
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DOI：
10.1007/978-3-662-09197-5_10
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发表时间：
1985
影响因子：
--
通讯作者：
A. Simpson;S. Smithers
中科院分区：
文献类型：
--
作者：
A. Simpson;S. Smithers
Schistosomes or blood flukes are macroscopic multicellular organisms which live in the vascular system of vertebrates. Several species are medically important parasites of man in tropical, developing countries where infection is transmitted by freshwater snails. The free-swimming cercarial stage of the parasite shed by the snails is able to penetrate host skin directly. After 3–4 days in the dermis, the young schistosomes or schistosomula begin their intravascular migration through the lungs to the hepatic portal system, where they eventually mature and come to live in the small mesenteric or pelvic veins. A mature female worm will deposit upwards of 100 eggs/day into the blood stream and it is the host’s immune granulomatous reaction to eggs lodged in the tissues which is largely responsible for the chronic, debilitating, and often fatal disease.
