An improved method for the palladium-catalyzed amination of aryl iodides.
An improved method for the palladium-catalyzed amination of aryl iodides.
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DOI：
10.1002/chin.200136081
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发表时间：
2001-03
期刊：
影响因子：
--
通讯作者：
Mayssam H. Ali;S. Buchwald
中科院分区：
文献类型：
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作者：
Mayssam H. Ali;S. Buchwald
在钯、合适的配体和Naot-Bu的存在下，芳基碘与胺偶联，以高产率得到相应的芳胺。当Cs(2)CO(3)被取代为碱时，功能化的芳基碘可以很好地得到相应的芳胺。
Aryl iodides are coupled with amines to give the corresponding arylamines in high yield in the presence of palladium, a suitable ligand, and NaOt-Bu. Functionalized aryl iodides give good yields of the corresponding arylamines when Cs(2)CO(3) is substituted as the base.