Forward conditioning with wheel running causes place aversion in rats

Forward conditioning with wheel running causes place aversion in rats
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DOI:
10.1016/j.beproc.2008.04.006
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发表时间:
2008-09-01
影响因子:
1.3
通讯作者:
Nakajima, Sadahiko
Nakajima, Sadahiko
中科院分区:
生物学4区
文献类型:
--
作者:
Masaki, Takahisa;Nakajima, Sadahiko

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作为条件刺激的独特腔室和作为非条件刺激的车轮运行的后向配对(即,跑室)可以在大鼠中产生条件性位置偏爱。本研究探讨了是否有这些刺激的前向条件反射程序(即,然后跑房间)会产生位置偏好或厌恶。将一只老鼠关在两个不同的房间中的一个里,然后有20或60分钟的跑步机会,但关在另一个房间里则没有。在该处理的四次重复之后(即,差异条件作用),进行选择偏好测试,其中大鼠可以自由进入两个室。这个选择测试表明,给予60分钟跑步机会的大鼠在跑步配对室中的时间比在非配对室中的时间少。也就是说,一个60分钟的运行机会后,限制在一个独特的商会造成条件性厌恶该商会后,四个配对试验。这一结果进行了讨论方面的服从过程理论的动机。(c)2008年爱思唯尔BY。版权所有
Backward pairings of a distinctive chamber as a conditioned stimulus and wheel running as an unconditioned stimulus (i.e., running-then-chamber) can produce a conditioned place preference in rats. The present study explored whether a forward conditioning procedure with these stimuli (i.e., chamber-thenrunning) would yield place preference or aversion. Confinement ofa rat in one oftwo distinctive chambers was followed by a 20- or 60-min running opportunity, but confinement in the other was not. After four repetitions of this treatment (i.e., differential conditioning), a choice preference test was given in which the rat had free access to both chambers. This choice test showed that the rats given 60-min running opportunities spent less time in the running-paired chamber than in the unpaired chamber. Namely, a 60-min running opportunity after confinement in a distinctive chamber caused conditioned aversion to that chamber after four paired trials. This result was discussed with regard to the opponent-process theory of motivation. (c) 2008 Elsevier BY. All rights reserved