Recruitment of HIF-1 a and HIF-2 a to common target genes is differentially regulated in neuroblastoma : HIF-2 a promotes an aggressive phenotype-猫眼课题宝

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Linda Holmquist-Mengelbier;E. Fredlund;Tobias Löfstedt;R. Noguera;S. Navarro;Helén Nilsson;A. Pietras;J. Vallon-Christersson;Å. Borg;K. Gradin;L. Poellinger;S. Påhlman

1分子医学部，实验室医学系，隆德大学，MAS大学医院，SE-205 02 Malmö，瑞典2病理学系，瓦伦西亚大学，医学院，瓦伦西亚，Avda Blasco Ibañez 17，46010 Valencia，西班牙3肿瘤学系，隆德大学，SE-221 00隆德，瑞典4细胞和分子生物学系，医学诺贝尔研究所，卡罗林斯卡医学院，SE-171 77斯德哥尔摩，瑞典5这些作者对这项工作做出了同等贡献。* 通信：sven. med.lu.se

1 Division of Molecular Medicine, Department of Laboratory Medicine, Lund University, University Hospital MAS, SE-205 02 Malmö, Sweden 2 Department of Pathology, University of Valencia, Medical School, Valencia, Avda Blasco Ibañez 17, 46010 Valencia, Spain 3 Department of Oncology, Lund University, SE-221 00 Lund, Sweden 4 Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, SE-171 77 Stockholm, Sweden 5 These authors contributed equally to this work. *Correspondence: sven.pahlman@med.lu.se

Recruitment of HIF-1 a and HIF-2 a to common target genes is differentially regulated in neuroblastoma : HIF-2 a promotes an aggressive phenotype

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