A novel antibacterial dental glass-ionomer cement.
A novel antibacterial dental glass-ionomer cement.
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DOI：
10.1111/j.1600-0722.2010.00770.x
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发表时间：
2010-10
影响因子：
1.9
通讯作者：
Y. Weng;Xia Guo;R. Gregory;D. Xie
中科院分区：
文献类型：
--
作者：
Y. Weng;Xia Guo;R. Gregory;D. Xie
本研究报告了一种新型的非沥滤性聚季铵盐（PQAS）抗菌玻璃离子水门汀的合成和评价。使用Fuji II LC骨水泥进行比较。抗压强度（CS）和变形链球菌活力分别用于评价强度和抗菌活性。在测试之前，所有样品在37摄氏度的蒸馏水中进行调节。在加入1- 30%PQAS后，两种水泥显示CS减少，Fuji II LC减少25-95%，实验水泥减少13-78%，S减少。对于Fuji II LC，40-79%，对于实验骨水泥，40-91%。实验骨水泥表现出较少的CS减少和较高的抗菌活性相比，富士II LC。结果还表明，水泥是永久抗菌的，没有浸出的PQAS。实验水泥似乎是一种临床上有吸引力的牙科修复材料，由于其高机械强度和永久抗菌功能，可用于长期的牙科修复。
This study reports the synthesis and evaluation of a novel non-leachable poly(quaternary ammonium salt) (PQAS)-containing antibacterial glass-ionomer cement. Fuji II LC cement was used for comparison. Compressive strength (CS) and Streptococcus mutans viability were used to evaluate strength and antibacterial activity, respectively. All specimens were conditioned in distilled water at 37 degrees C before testing. After the addition of 1-30% PQAS, both cements showed a reduction in CS, of 25-95% for Fuji II LC and 13-78% for the experimental cement, and a reduction in S. mutans viability, of 40-79% for Fuji II LC and 40-91% for the experimental cement. The experimental cement showed less CS reduction and higher antibacterial activity compared with Fuji II LC. The result also indicates that the cements are permanently antibacterial, with no leaching of PQAS. It appears that the experimental cement is a clinically attractive dental restorative that can be potentially used for longlasting restorations as a result of its high mechanical strength and permanent antibacterial function.