A MODEL OF THE STIMULATION OF A NERVE-FIBER BY ELECTROMAGNETIC INDUCTION
A MODEL OF THE STIMULATION OF A NERVE-FIBER BY ELECTROMAGNETIC INDUCTION
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DOI：
10.1109/10.55662
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发表时间：
1990-06-01
影响因子：
4.6
通讯作者：
BASSER, PJ
中科院分区：
文献类型：
--
作者：
ROTH, BJ;BASSER, PJ
提出了一个模型来解释电磁感应神经刺激的物理学。麦克斯韦方程预测了当电容器通过刺激线圈放电时产生的感应电场分布。非线性Hodgkin-Huxley电缆模型描述了神经纤维对此感应电场的响应。一旦线圈的位置、方向和形状被给定，并且刺激电路的电阻、电容和初始电压被指定，该模型预测作为距离和时间的函数的纤维的所得跨膜电位。它示出的神经纤维是由平行于纤维的感应电场的分量的梯度刺激的，其超极化或去极化膜，并且可以刺激动作电位。该模型预测了复杂的动力学，如动作电位湮灭和分散。<>
A model is presented to explain the physics of nerve stimulations by electromagnetic induction. Maxwell's equations predict the induced electric field distribution that is produced when a capacitor is discharged through a stimulating coil. A nonlinear Hodgkin-Huxley cable model describes the response of the nerve fiber to this induced electric field. Once the coil's position, orientation, and shape are given and the resistance, capacitance, and initial voltage of the stimulating circuit are specified, this model predicts the resulting transmembrane potential of the fiber as a function of distance and time. It is shown that the nerve fiber is stimulated by the gradient of the component of the induced electric field that is parallel to the fiber, which hyperpolarizes or depolarizes the membrane and may stimulate an action potential. The model predicts complicated dynamics such as action potential annihilation and dispersion.<>