Strength in diversity: Intra-cellular metabolite sharing enhances longevity.
Strength in diversity: Intra-cellular metabolite sharing enhances longevity.
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多样性的优势：细胞内代谢物共享可延长寿命。
DOI：
10.1016/j.cell.2022.12.012
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发表时间：
2023
期刊：
影响因子：
64.5
通讯作者：
Anderson,RozalynM
中科院分区：
文献类型：
--
作者：
Lamming,DudleyW;Anderson,RozalynM
我们对细胞生物学的许多基础知识来自于对芽殖酵母的研究，芽殖酵母通常被描述为一种简单的单细胞真核模型。在本期的《细胞》杂志中，Correia-Melo et al.描述了酵母生物学的一个未被重视的特征，涉及细胞内代谢物交换，其中细胞作为群落的一部分进行适应和响应，并继续表明与甲硫氨酸代谢相关的资源共享增强了合作细胞的寿命。
Much of our foundational knowledge of cellular biology comes from studies in budding yeast, often described as a simple unicellular eukaryotic model. In this issue ofCell, Correia-Melo et al. describe an unappreciated feature of yeast biology involving intra-cellular metabolite exchange, where cells adapt and respond as part of a community, and go on to show that sharing of resources linked to methionine metabolism enhances longevity of cooperating cells.