Designing optimal HIV-vaccine T-cell responses.

Designing optimal HIV-vaccine T-cell responses.
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设计最佳的 HIV 疫苗 T 细胞反应。

DOI:
10.1097/coh.0000000000000313
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发表时间:
2016
影响因子:
4.1
通讯作者:
Streeck,Hendrik
Streeck,Hendrik
中科院分区:
医学3区
文献类型:
--
作者:
Streeck,Hendrik

文献摘要

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很明显,所有疫苗的效力都依赖于细胞组分,以直接杀死病毒感染的细胞或为有效B细胞应答的发展提供重要的辅助信号。最近的疫苗试验对该领域产生了重大影响,并正在指导艾滋病毒疫苗设计的新方法。
It is apparent that all vaccines depend for their efficacy on a cellular component either to directly kill virally infected cells or to provide important helper signals for the development of efficacious B-cell responses. Recent vaccine trials have had a major impact on the field and are guiding new approaches for HIV vaccine design.