Dietary weight loss and exercise interventions effects on quality of life in overweight/obese postmenopausal women: a randomized controlled trial.
Dietary weight loss and exercise interventions effects on quality of life in overweight/obese postmenopausal women: a randomized controlled trial.
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DOI：
10.1186/1479-5868-8-118
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发表时间：
2011-10-25
期刊：
影响因子：
--
通讯作者：
McTiernan A
中科院分区：
文献类型：
--
作者：
Imayama I;Alfano CM;Kong A;Foster-Schubert KE;Bain CE;Xiao L;Duggan C;Wang CY;Campbell KL;Blackburn GL;McTiernan A
虽然针对多种生活方式行为的生活方式干预在预防不健康的体重增加和慢性疾病方面比干预单一行为更有效，但很少有研究比较饮食和/或运动干预对健康相关生活质量（HRQOL）的个体和综合影响。此外，这些生活方式干预如何影响HRQOL的机制尚不清楚。本研究的主要目的是检查饮食减肥和/或运动干预对HRQOL和心理社会因素（抑郁，焦虑，压力，社会支持）的个体和综合影响。次要目的是研究HRQOL变化的预测因素。本研究为随机对照试验。超重/肥胖的绝经后妇女被随机分配到12个月的饮食减肥（n = 118），中度至剧烈的有氧运动（225分钟/周，n = 117），饮食和运动相结合（n = 117），或控制（n = 87）。在基线和12个月时评估人口统计学、健康和人体测量信息、有氧健身、HRQOL（SF-36）、压力（感知压力量表）、抑郁[简明症状量表（BSI）-18]、焦虑（BSI-18）和社会支持（医疗结局研究社会支持调查）。使用协方差分析比较HRQOL和心理社会因素的12个月变化，调整基线评分。多元回归用于评估HRQOL变化的预测因素。HRQOL和心理社会因素的12个月变化因干预组而异。饮食+运动组合组改善了HRQOL的4个方面（身体功能、身体角色、活力和心理健康）和压力（与对照组相比，p ≤ 0.01）。饮食组增加了活力评分（p < 0.01 vs. control），而运动组HRQOL与对照组相比没有不同的变化。然而，无论干预组，体重减轻预测增加的身体功能，身体角色，活力和心理健康，而增加有氧健身预测改善身体功能。在调整了体重和有氧健身的变化后，抑郁、压力和社会支持的积极变化与HRQOL的增加独立相关。饮食和运动相结合的干预对HRQOL和心理健康有积极的影响，这可能比单独运动或饮食更大。体重、有氧健身和心理社会因素的改善可能介导HRQOL的干预效果。
Although lifestyle interventions targeting multiple lifestyle behaviors are more effective in preventing unhealthy weight gain and chronic diseases than intervening on a single behavior, few studies have compared individual and combined effects of diet and/or exercise interventions on health-related quality of life (HRQOL). In addition, the mechanisms of how these lifestyle interventions affect HRQOL are unknown. The primary aim of this study was to examine the individual and combined effects of dietary weight loss and/or exercise interventions on HRQOL and psychosocial factors (depression, anxiety, stress, social support). The secondary aim was to investigate predictors of changes in HRQOL. This study was a randomized controlled trial. Overweight/obese postmenopausal women were randomly assigned to 12 months of dietary weight loss (n = 118), moderate-to-vigorous aerobic exercise (225 minutes/week, n = 117), combined diet and exercise (n = 117), or control (n = 87). Demographic, health and anthropometric information, aerobic fitness, HRQOL (SF-36), stress (Perceived Stress Scale), depression [Brief Symptom Inventory (BSI)-18], anxiety (BSI-18) and social support (Medical Outcome Study Social Support Survey) were assessed at baseline and 12 months. The 12-month changes in HRQOL and psychosocial factors were compared using analysis of covariance, adjusting for baseline scores. Multiple regression was used to assess predictors of changes in HRQOL. Twelve-month changes in HRQOL and psychosocial factors differed by intervention group. The combined diet + exercise group improved 4 aspects of HRQOL (physical functioning, role-physical, vitality, and mental health), and stress (p ≤ 0.01 vs. controls). The diet group increased vitality score (p < 0.01 vs. control), while HRQOL did not change differently in the exercise group compared with controls. However, regardless of intervention group, weight loss predicted increased physical functioning, role-physical, vitality, and mental health, while increased aerobic fitness predicted improved physical functioning. Positive changes in depression, stress, and social support were independently associated with increased HRQOL, after adjusting for changes in weight and aerobic fitness. A combined diet and exercise intervention has positive effects on HRQOL and psychological health, which may be greater than that from exercise or diet alone. Improvements in weight, aerobic fitness and psychosocial factors may mediate intervention effects on HRQOL.
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影响因子：
120.7
作者：
Flegal, Katherine M.;Carroll, Margaret D.;Curtin, Lester R.
通讯作者：
Curtin, Lester R.
影响因子：
158.5
作者：
Knowler, WC;Barrett-Connor, E;Nathan, DM
通讯作者：
Nathan, DM
影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
4.9
作者：
Kaukua, J;Pekkarinen, T;Mustajoki, P
通讯作者：
Mustajoki, P
DOI：
10.1186/1479-5868-6-9
发表时间：
2009-02-09
影响因子：
8.7
作者：
Palmeira, Antonio L.;Markland, David A.;Teixeira, Pedro J.
通讯作者：
Teixeira, Pedro J.