Mitochondrial manoeuvres: latest insights and hypotheses on mitochondrial partitioning during mitosis in Saccharomyces cerevisiae.
Mitochondrial manoeuvres: latest insights and hypotheses on mitochondrial partitioning during mitosis in Saccharomyces cerevisiae.
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线粒体操纵：关于酿酒酵母有丝分裂过程中线粒体分配的最新见解和假设。
DOI：
10.1002/bies.201000083
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Pon,LizaA
中科院分区：
文献类型：
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作者：
Peraza-Reyes,Leonardo;Crider,DavidG;Pon,LizaA
线粒体和其他细胞器的运动和位置控制与芽殖酵母（Saccharomyces cerevisiae）的细胞周期进程相协调。最近的研究揭示了当线粒体遗传存在严重缺陷时，会抑制胞质分裂的检查点。一个已建立的检查点信号通路，有丝分裂出口网络（MEN），参与这一过程。在这里，我们描述了在芽殖酵母遗传过程中的线粒体运动性，遗传过程中线粒体质量控制的新证据，线粒体和其他细胞器的细胞器遗传检查点。
Movement and positional control of mitochondria and other organelles are coordinated with cell cycle progression in the budding yeast,Saccharomyces cerevisiae. Recent studies have revealed a checkpoint that inhibits cytokinesis when there are severe defects in mitochondrial inheritance. An established checkpoint signaling pathway, the mitotic exit network (MEN), participates in this process. Here, we describe mitochondrial motility during inheritance in budding yeast, emerging evidence for mitochondrial quality control during inheritance, and organelle inheritance checkpoints for mitochondria and other organelles.