Complementary α-alkylation approaches for a sterically hindered spiro[pyrazolopyranpiperidine]ketone
Complementary α-alkylation approaches for a sterically hindered spiro[pyrazolopyranpiperidine]ketone
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DOI：
10.1016/j.tetlet.2012.03.030
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发表时间：
2012-05-16
影响因子：
1.8
通讯作者：
Vrieze, Derek
中科院分区：
文献类型：
--
作者：
Limberakis, Chris;Li, Jianke;Vrieze, Derek
互补-烷基化方法被用来衍生一个立体受阻螺旋[吡唑吡哌啶]酮。更具体地说，在DMPU和醛醇缩合的存在下，烯醇醇烷基化被用来传递这些化合物。(C) 2012 Elsevier Ltd.版权所有。
Complementary alpha-alkylation methods are used to derivatize a sterically hindered spiro[pyrazolopyranpiperidine]ketone. More specifically, enolate alkylations in the presence of DMPU and aldol condensations are employed to deliver these compounds. (C) 2012 Elsevier Ltd. All rights reserved.