Anemia is an independent predictor of mortality after percutaneous coronary intervention
Anemia is an independent predictor of mortality after percutaneous coronary intervention
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DOI：
10.1016/j.jacc.2004.04.047
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发表时间：
2004-08-04
影响因子：
24
通讯作者：
Sharma, SK
中科院分区：
文献类型：
--
作者：
Lee, PC;Kini, AS;Sharma, SK
本研究的目的是评估贫血是否是介入治疗过程中风险增加和经皮冠状动脉介入治疗（PCI）后中期生存率差的标志。背景贫血与心力衰竭和心肌梗死（MI）患者死亡率增加的风险相关。116例连续PCI患者，基于介入手术前的血红蛋白（Hb）值。根据基线Hb水平（g/l）将患者分为三组：Hb 12 =无贫血。结果贫血的存在与较高的30天主要不良心脏事件、PCI术后肌钙蛋白峰值和肌酸激酶MB分数以及较长的住院时间相关。在控制多个协变量后，贫血组与无贫血组相比，1年生存率存在显著差异（Hb 10至12的校正风险比：1.5 [95%置信区间1.3至1.8]; Hb 10至12的校正风险比：1.5 [95%置信区间1.3至1.8]）。
OBJECTIVES The aim of the present study was to assess whether anemia is a marker of increased risk during interventional procedure and poor midterm survival after percutaneous coronary intervention (PCI).BACKGROUND Anemia is associated with increased risk of mortality in patients with heart failure and myocardial infarction (MI).METHODS We examined the outcomes of 6,116 consecutive PCI patients based on the hemoglobin (Hb) value before the interventional procedure. Patients were divided into three groups based on the baseline Hb level (g/l): Hb 12 = no anemia.RESULTS The presence of anemia is associated with higher 30-day major adverse cardiac events, post-PCI peak troponin and creatine kinase-MB fraction, and a longer length of stay. After controlling for multiple covariates, significant difference in one-year survival was noted in the anemic groups compared with no anemia group (adjusted hazard ratio for Hb 10 to 12: 1.5 [95% confidence interval 1.3 to 1.8]; for Hb