Decreased Paired‐pulse Inhibition in the Dentate Gyrus of the Brain in Rats Exposed to 1‐Bromopropane Vapor
Decreased Paired‐pulse Inhibition in the Dentate Gyrus of the Brain in Rats Exposed to 1‐Bromopropane Vapor
复制标题
暴露于 1-溴丙烷蒸气的大鼠大脑齿状回的成对脉冲抑制减少
DOI：
10.1539/joh.42.149
复制
发表时间：
2000
影响因子：
3
通讯作者：
K. Arashidani
中科院分区：
文献类型：
--
作者：
Y. Fueta;T. Ishidao;T. Kasai;H. Hori;K. Arashidani
，但还没有研究集中于1-BP对大脑神经功能的影响。本文初步研究了吸入1-BP对大鼠脑片齿状回(DG)神经元功能的影响，并观察到DG的异常反应。因此，Wethern开始对行为变化中涉及的功能变化感兴趣。本研究的目的是研究亚慢性暴露于1-BP的大鼠脑内神经元兴奋性的变化。配对脉冲分析已被广泛用于研究生理学中抑制丘脑兴奋性的变化
, but no studies have focused on theeffects of 1-BP on the neuronal function in the brain. Westudied the effects of 1-BP inhalation on neuronal functionand observed abnormal responses in the dentate gyrus(DG) of brain slices obtained from rats with convulsioninduced by 1-BP inhalation in our preliminary study. Wetherfore became interested in functional changes involvedin behavioral changes. The aim of this study was toinvestigate changes in neuronal excitability in the brainof rats subchronically exposed to 1-BP. Paired-pulseanalysis has been widely used to study changes inhippocampal excitability in physiological