NUCLEOTIDE-SEQUENCE OF THE YEAST SUC2 GENE FOR INVERTASE
NUCLEOTIDE-SEQUENCE OF THE YEAST SUC2 GENE FOR INVERTASE
复制标题
DOI：
10.1093/nar/11.6.1943
复制
发表时间：
1983-01-01
影响因子：
14.9
通讯作者：
CARLSON, M
中科院分区：
文献类型：
--
作者：
TAUSSIG, R;CARLSON, M
酵母SUC2基因是分泌型和细胞内型转化酶的结构基因。我们已经确定了编码区以及 5' 和 3' 侧翼区的核苷酸序列。分泌型转化酶的含有信号肽的前体和细胞内转化酶的编码区在SUC2基因内的不同起始密码子处开始，但共享相同的阅读框。从核苷酸序列预测的两种形式的转化酶的氨基酸序列与纯化酶的性质一致。确定了分泌型转化酶糖基化的潜在位点。
The yeastSUC2gene is a structural gene for both the secreted and intracellular forms of invertase. We have determined the nucleotide sequence of the coding region and the 5’ and 3’ flanking regions. The coding regions for the signal peptide-containing precursor to secreted invertase and for the intracellular invertase begin at different initiation codons within theSUC2qene but share the same reading frame. The amino acid sequences predicted for the two forms of invertase from the nucleotide sequence are consistent with the properties of the purified enzymes. Potential sites for glycosylation of the secreted invertase are identified.