A 256-element ultrasonic phased array system for the treatment of large volumes of deep seated tissue
A 256-element ultrasonic phased array system for the treatment of large volumes of deep seated tissue
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DOI：
10.1109/58.796130
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发表时间：
1999-09-01
影响因子：
3.6
通讯作者：
Hynynen, K
中科院分区：
文献类型：
--
作者：
Daum, DR;Hynynen, K
A 256-element phased array has been designed, constructed, and tested for ablative treatment of large focal volumes of deep seated tissue. The array was constructed fi om a 1.1-MHz, 1-3 composite piezoelectric spherical shell with a la-cm radius of curvature and a 12-cm diameter. The array was tested to determine its electroacoustic efficiency and inter-element coupling under high acoustic power conditions. A series of in vivo porcine experiments demonstrated the ability to produce deep seated tissue lesions in thigh muscle using the large scale phased array. The array was used to heat and coagulate tissue volumes > 5 cm(3) in a single ultrasound exposure using multiple foci and temporally scanned power deposition patterns. The spatial and temporal experimental results for large, heated focal volumes correlated very well with the simulated temperature response model for homogeneous tissue. A 25-cm(3) tissue volume was coagulated in a 90-min period using overlapping large ultrasound exposures.
