The anterior cingulate and error avoidance
The anterior cingulate and error avoidance
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DOI：
10.1523/jneurosci.0369-06.2006
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发表时间：
2006-05-03
影响因子：
5.3
通讯作者：
Garavan, H
中科院分区：
文献类型：
--
作者：
Magno, E;Foxe, JJ;Garavan, H
前扣带皮层在监测、评估和纠正行为中的确切作用仍然不清楚，尽管有许多理论和大量经验数据表明它与认知控制有关。目前的事件相关功能磁共振成像研究能够通过允许受试者拒绝试验以避免错误来将监测与错误特异性功能分离。扣带回和左背外侧前额叶活动是最大的拒绝试验，但可比的正确和错误的试验，而错误的具体反应，观察到在双边trouble。扣带回和核之间也观察到分离，后者更积极的错误比拒绝试验。这些结果表明，扣带回的功能作用是不是特别的错误，而是有关的评价功能有关的在线行为调整服务，以避免损失。
The precise role of the anterior cingulate cortex in monitoring, evaluating, and correcting behavior remains unclear despite numerous theories and much empirical data implicating it in cognitive control. The present event-related functional magnetic resonance imaging study was able to separate monitoring from error-specific functions by allowing subjects to reject a trial so as to avoid errors. Cingulate and left dorsolateral prefrontal activity was greatest on rejection trials but comparable for correct and error trials, whereas an error-specific response was observed in bilateral insula. A dissociation was also observed between the cingulate and the nucleus accumbens with the latter more active for error than reject trials. These results reveal that the functional role of the cingulate is not particular to errors but instead is related to an evaluative function concerned with on-line behavioral adjustment in the service of avoiding losses.