Purpose in life and reduced risk of myocardial infarction among older US adults with coronary heart disease: a two-year follow-up
Purpose in life and reduced risk of myocardial infarction among older US adults with coronary heart disease: a two-year follow-up
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DOI：
10.1007/s10865-012-9406-4
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发表时间：
2013-04-01
影响因子：
3.1
通讯作者：
Peterson, Christopher
中科院分区：
文献类型：
--
作者：
Kim, Eric S.;Sun, Jennifer K.;Peterson, Christopher
本研究在调整了相关的社会人口学、行为学、生物学和心理学因素后，探讨了老年冠心病患者的生活目的是否与心肌梗死相关。使用了健康与退休研究的前瞻性数据，这是一项针对50岁以上美国成年人的全国代表性小组研究。对1,546名基线时患有冠心病的人进行了分析。在2年随访期间，生活目标越高，发生心肌梗死的几率越低。在生活目标的六点测量中，每增加一个单位与心肌梗死的多变量校正比值比0.73相关（95%CI，0.57-0.93，P = 0.01）。在控制了冠心病严重程度、自评健康状况和一系列可能的混淆因素后，这种关联仍然显著。在美国老年冠心病患者中，更高的生活目标可能在预防心肌梗死方面发挥重要作用。
This study examined whether purpose in life was associated with myocardial infarction among a sample of older adults with coronary heart disease after adjusting for relevant sociodemographic, behavioral, biological, and psychological factors. Prospective data from the Health and Retirement Study-a nationally representative panel study of American adults over the age of 50-were used. Analyses were conducted on the subset of 1,546 individuals who had coronary heart disease at baseline. Greater baseline purpose in life was associated with lower odds of having a myocardial infarction during the 2-year follow-up period. On a six-point purpose in life measure, each unit increase was associated with a multivariate-adjusted odds ratio of 0.73 for myocardial infarction (95% CI, 0.57-0.93, P = .01). The association remained significant after controlling for coronary heart disease severity, self-rated health, and a comprehensive set of possible confounds. Higher purpose in life may play an important role in protecting against myocardial infarction among older American adults with coronary heart disease.