Home based neuromuscular electrical stimulation as a new rehabilitative strategy for severely disabled patients with chronic obstructive pulmonary disease (COPD)
Home based neuromuscular electrical stimulation as a new rehabilitative strategy for severely disabled patients with chronic obstructive pulmonary disease (COPD)
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DOI：
10.1136/thorax.57.4.333
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发表时间：
2002-04-01
期刊：
影响因子：
10
通讯作者：
Clark, CJ
中科院分区：
文献类型：
--
作者：
Neder, JA;Sword, D;Clark, CJ
背景资料：在重度慢性阻塞性肺疾病（COPD）患者中，通过神经肌肉电刺激（LAMES）对特定运动肌群进行被动训练可能比全身运动耐受性更好。据推测，这种新的策略将特别有效地改善功能障碍和随之而来的残疾，这是终末期COPD患者的特征。15例晚期COPD患者（9名男性）被随机分配到以家庭为基础的6周股四头肌LAMES训练计划，（第1组，n=9，FEV 1 =预测值的38.0（9.6）%）或接受LAMES之前的6周控制期（第2组，n=6，FEV 1 =预测值的39.5（13.3）%）。膝关节伸肌力量和耐力，全身运动能力，健康相关的生活质量（慢性呼吸道疾病问卷，CRDQ）进行了assessed.Results：所有患者都能够成功地完成LAMES训练计划，即使在存在急性加重（n=4）。训练与肌肉功能、最大和耐力运动耐量以及CRDQ的呼吸困难领域的显著改善相关（p
Background: Passive training of specific locomotor muscle groups by means of neuromuscular electrical stimulation (LAMES) might be better tolerated than whole body exercise in patients with severe chronic obstructive pulmonary disease (COPD). It was hypothesised that this novel strategy would be particularly effective in improving functional impairment and the consequent disability which characterises patients with end stage COPD.Methods: Fifteen patients with advanced COPD (nine men) were randomly assigned to either a home based 6 week quadriceps femoris LAMES training programme (group 1, n=9, FEV1=38.0 (9.6)% of predicted) or a 6 week control period before receiving LAMES (group 2, n=6, FEV1=39.5 (13.3)% of predicted). Knee extensor strength and endurance, whole body exercise capacity, and health related quality of life (Chronic Respiratory Disease Questionnaire, CRDQ) were assessed.Results: All patients were able to complete the LAMES training programme successfully, even in the presence of exacerbations (n=4). Training was associated with significant improvements in muscle function, maximal and endurance exercise tolerance, and the dyspnoea domain of the CRDQ (p