Palladium-catalyzed intermolecular decarboxylative coupling of 2-phenylbenzoic acids with alkynes via C-H and C-C bond activation.
Palladium-catalyzed intermolecular decarboxylative coupling of 2-phenylbenzoic acids with alkynes via C-H and C-C bond activation.
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DOI：
10.1021/ja106130r
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发表时间：
2010-09
影响因子：
15
通讯作者：
Cong-Hui Wang;S. Rakshit;F. Glorius
中科院分区：
文献类型：
--
作者：
Cong-Hui Wang;S. Rakshit;F. Glorius
报道了钯催化2-苯基苯甲酸与炔烃的分子间[4+2]环化反应的新方法。结果表明，吖啶类化合物是提高反应效率的关键。菲的衍生物以中等到良好的产率形成，没有偶联(假)卤化物或有机金属物种。
A novel protocol for palladium-catalyzed intermolecular formal [4 + 2] annulation of 2-phenylbenzoic acids with alkynes is described. Acridine is shown to be essential for the high reaction efficiency. Phenanthrene derivatives are formed in moderate to good yields without coupling (pseudo)halides or organometallic species.