Challenge of Neurorehabilitation for Cerebellar Degenerative Diseases
Challenge of Neurorehabilitation for Cerebellar Degenerative Diseases
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DOI：
10.1007/s12311-011-0327-5
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发表时间：
2012-06-01
期刊：
影响因子：
3.5
通讯作者：
Miyai, Ichiro
中科院分区：
文献类型：
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作者：
Miyai, Ichiro
小脑共济失调康复试验测试了强化康复是否改善了42例退行性小脑疾病患者的共济失调、步态和日常生活活动（ADL）。他们被随机分配到即时干预组或延迟进入对照组。即刻组接受为期4周的1 h物理治疗和1 h作业治疗，延迟进入对照组在延迟4周后接受同样的干预措施。即刻组在共济失调、步态速度和ADL方面的功能改善显著高于对照组。共济失调和步态速度的改善分别在干预后12周和24周持续。应研究能在较长时期内产生有意义收益的进一步战略。
Cerebellar Ataxia Rehabilitation trial tested if intensive rehabilitation improved ataxia, gait, and activities of daily living (ADLs) in 42 patients with degenerative cerebellar diseases. They were randomly assigned to the immediate intervention group or the delayed-entry control group. The immediate group received 1 h physical and 1 h occupational therapy for 4 weeks and delayed-entry control group received the same intervention after 4-week delay. The immediate group showed significantly greater functional gains in ataxia, gait speed, and ADLs than control. The improvements in ataxia and gait speed were sustained at 12 and 24 weeks after the intervention, respectively. Further strategies inducing meaningful gains for a longer period should be investigated.