SEGMENTAL DISTRIBUTION OF BITHORAX COMPLEX PROTEINS DURING DROSOPHILA DEVELOPMENT
SEGMENTAL DISTRIBUTION OF BITHORAX COMPLEX PROTEINS DURING DROSOPHILA DEVELOPMENT
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DOI：
10.1038/313545a0
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发表时间：
1985-01-01
期刊：
影响因子：
64.8
通讯作者：
HOGNESS, DS
中科院分区：
文献类型：
--
作者：
BEACHY, PA;HELFAND, SL;HOGNESS, DS
Ubx和bxd转录单位在D.黑腹菌的节段分布和核定位的蛋白质编码的Ubx单元的免疫荧光染色与抗体对含有Ubx编码序列的融合蛋白。野生型和突变体的分布是一致的模型，其中的蛋白质编码功能的域来自Ubx单元和调节的bxd单元。
The Ubx and bxd transcription units comprise a single functional domain in the bithorax complex of D. melanogaster. The segmental distributions and nuclear localization of proteins encoded by the Ubx unit were determined by immunofluorescence staining with antibodies raised against a fusion protein containing Ubx coding sequences. Wild-type and mutant distributions are consistent with a model in which the protein-coding functions of the domain derive from the Ubx unit and are regulated by the bxd unit.