Quantitative skeletal muscle ultrasound: Diagnostic value in childhood neuromuscular disease
Quantitative skeletal muscle ultrasound: Diagnostic value in childhood neuromuscular disease
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DOI：
10.1016/j.nmd.2007.03.008
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发表时间：
2007-07-01
影响因子：
2.8
通讯作者：
Zwarts, M. J.
中科院分区：
文献类型：
--
作者：
Pillen, S.;Verrips, A.;Zwarts, M. J.
在这项研究中，我们调查了150名连续转诊的疑似神经肌肉疾病症状儿童的定量骨骼肌超声检查的诊断价值。肌肉厚度和定量测定的回声强度的四块肌肉和体内这些变量的分布进行了检查。结果如下：有和没有神经肌肉疾病的患者可以区分阳性预测值为91%，阴性预测值为86%。使用体内病理分布模式，神经源性疾病患者可与肌病和非神经肌肉疾病区分开来，阳性预测值为86%，阴性预测值为84%。结论：骨骼肌超声是诊断儿童神经肌肉疾病的一种良好、实用和非侵入性的辅助手段，能够区分有无神经肌肉疾病的儿童以及神经源性疾病和肌病，具有较高的预测价值。(C)2007 Elsevier B.V.保留所有权利。
In this study we investigated the diagnostic value of quantitative skeletal muscle ultrasonography in 150 consecutively referred children with symptoms suspect for a neuromuscular disorder. Muscle thickness and quantitatively determined echo intensity of four muscles and the distribution of these variables within the body were examined. Results: Patients with and without a neuromuscular disorder could be discriminated with a positive predictive value of 91% and a negative predictive value of 86%. Patients with a neurogenic disorder could be distinguished from myopathies and non-neuromuscular disorders with a positive predictive value of 86% and a negative predictive of 84%, using the pattern of distribution of pathology within the body. Conclusions: Skeletal muscle ultrasound is a good, practical and non-invasive aid in the diagnosis of neuromuscular disorders in children, that is able to discriminate between children with and without a neuromuscular disorder and between neurogenic disorders and myopathies with high predictive values. (C) 2007 Elsevier B.V. All rights reserved.