Mobile Microplates for Morphological Control and Assembly of Individual Neural Cells

Mobile Microplates for Morphological Control and Assembly of Individual Neural Cells
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DOI:
10.1002/adhm.201500782
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发表时间:
2016-02-18
影响因子:
10
通讯作者:
Takeuchi, Shoji
Takeuchi, Shoji
中科院分区:
工程技术1区
文献类型:
--
作者:
Yoshida, Shotaro;Teshima, Tetsuhiko;Takeuchi, Shoji

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描述了一种微制造装置,该装置使培养的单个神经细胞的形态控制和组装成为可能。形态学控制的单个神经细胞的组装使神经工程师能够以单细胞分辨率设计体外神经回路。与传统的细胞模式技术相比,该设备允许以可复制的方式高度精确地定位神经体和神经突。
A microfabricated device that enables morphological control and assembly of cultured single neural cells is described. Assembly of morphologically controlled single neural cells allows neuroengineers to design in vitro neural circuits with a single-cell resolution. Compared to conventional cell-patterning techniques, the device allows for the highly precise positioning of neural somas and neurites in a reproducible fashion.