Obese parturients have lower epidural local anaesthetic requirements for analgesia in labour
Obese parturients have lower epidural local anaesthetic requirements for analgesia in labour
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DOI：
10.1093/bja/aei284
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发表时间：
2006-01-01
影响因子：
9.8
通讯作者：
Columb, MO
中科院分区：
文献类型：
--
作者：
Panni, MK;Columb, MO
背景没有研究比较肥胖和正常产妇的局部麻醉要求。肥胖与剖腹产的发生率较高有关，在肥胖产科患者中也发现了较高水平的硬膜外阻滞，这表明他们可能需要较少的局部麻醉。本研究的目的是评估布比卡因用于肥胖和非肥胖产妇的最小局部镇痛浓度（MLAC）。其他健康产妇（n=32）要求硬膜外镇痛入组本上下序贯分配研究。女性处于活跃分娩期（宫颈扩张3-6 cm），视觉模拟疼痛评分（VAPS）> 40/100 mm。BMI > 30 kg m（-2）的受试者被分配到肥胖组，
Background. There are no studies comparing local anaesthetic requirements for obese and normal parturients. Obesity has been associated with a higher incidence of Caesarean section and higher levels of epidural block have also been found in obese obstetric patients, suggesting they may require less local anaesthetic. The aim of our study was to estimate the minimum local analgesic concentration (MLAC) of bupivacaine for obese and non-obese parturients.Methods. Otherwise healthy parturients (n=32) requesting epidural analgesia were enrolled in this up-down sequential allocation study. Women were in active labour (3-6 cm cervical dilatation) with visual analogue pain scores (VAPS) > 40/100 mm. Subjects with BMI > 30 kg m(-2) were allocated to the obese group and BMI