Multichannel DC SQUID sensor array for biomagnetic applications
Multichannel DC SQUID sensor array for biomagnetic applications
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适用于生物磁应用的多通道 DC SQUID 传感器阵列
DOI：
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发表时间：
1991
期刊：
影响因子：
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通讯作者：
K. Abraham
中科院分区：
文献类型：
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作者：
H. Hoenig;G. Daalmans;L. Bär;F. Bömmel;A. Paulus;D. Uhl;H. Weisse;S. Schneider;H. Seifert;H. Reichenberger;K. Abraham
研制了一种用于脑和心脏医学诊断的生物磁多通道系统。37个轴向一阶梯度计（制造为柔性超导印刷电路）布置在直径为19 cm的圆形平面阵列中。另外，提供了三个正交磁力计。DC SQUID采用全铌技术制造，10个在一个芯片上。传感器系统在屏蔽室中运行，屏蔽室中有两层软磁材料和一层铝。日常噪声水平为10 fT/Hz/sup 1/2/，频率高于10 Hz。在正常的城市环境中运行的两年内，已经证明了有用的临床应用（例如，癫痫和心律失常）。第一次电流源的零星事件引起癫痫或室性期前收缩已被定位从相干记录完整的生物磁场分布与毫米的空间分辨率和1毫秒的时间分辨率。
A biomagnetic multichannel system for medical diagnosis of the brain and heart has been developed. 37 axial first order gradiometers (manufactured as flexible superconducting printed circuits) are arranged in a circular flat array of 19 cm in diameter. Additionally, three orthogonal magnetometers are provided. The DC SQUIDs are fabricated in all-Nb technology, ten on a chip. The sensor system is operated in a shielded room with two layers of soft magnetic material and one layer of Al. The everyday noise level is 10 fT/Hz/sup 1/2/ at frequencies above 10 Hz. Within two years of operation in a normal urban surrounding, useful clinical applications have been demonstrated (e.g., for epilepsy and heart arrhythmias). For the first time current sources of sporadic events causing epilepsy or ventricular extrasystoles have been localized from coherent recordings of complete biomagnetic field distributions with spatial resolution of millimeters and temporal resolution of 1 ms.