Elucidating early mechanisms of developmental psychopathology: The case of prenatal smoking and disruptive behavior
Elucidating early mechanisms of developmental psychopathology: The case of prenatal smoking and disruptive behavior
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DOI：
10.1111/j.1467-8624.2006.00909.x
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发表时间：
2006-07-01
影响因子：
4.6
通讯作者：
Carter, Alice S.
中科院分区：
文献类型：
--
作者：
Wakschlag, Lauren S.;Leventhal, Bennett L.;Carter, Alice S.
产前吸烟与破坏性行为障碍之间存在着密切的联系，但人们对这种行为在早期发育中的出现知之甚少。产前吸烟和假设的行为前体破坏性行为的幼儿（N=93）的关联进行了测试。暴露的幼儿表现出非典型的行为模式，包括（1）从18个月到24个月，不断升级的外化问题和（2）观察到难以调节行为，以回应社会线索。具体说明与安全相关的行为是产生可检验的假设的第一步，假设的影响机制。虽然目前尚不清楚产前暴露是否在破坏性行为的出现中起着病因学作用，但非典型的破坏性相关行为模式在生命的最初几年是明显的，并表现出发育的连贯性。
There is a robust association between prenatal smoking and disruptive behavior disorders, but little is known about the emergence of such behaviors in early development. The association of prenatal smoking and hypothesized behavioral precursors to disruptive behavior in toddlers (N=93) was tested. Exposed toddlers demonstrated atypical behavioral patterns, including (1) escalating externalizing problems from 18 to 24 months and (2) observed difficulty modulating behavior in response to social cues. Specification of exposure-related behaviors is a first step toward generating testable hypotheses about putative mechanisms of effect. While it remains unclear whether prenatal exposure plays an etiologic role in the emergence of disruptive behavior, atypical exposure-related behavioral patterns are evident in the first years of life and demonstrate developmental coherence.