ANALYSES OF DIPLOTENE CHIASMA FREQUENCIES IN MOUSE OOCYTES AND SPERMATOCYTES IN RELATION TO AGING AND SEXUAL DIMORPHISM
ANALYSES OF DIPLOTENE CHIASMA FREQUENCIES IN MOUSE OOCYTES AND SPERMATOCYTES IN RELATION TO AGING AND SEXUAL DIMORPHISM
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DOI：
10.1159/000131302
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发表时间：
1979-01-01
期刊：
影响因子：
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通讯作者：
FANG, JS
中科院分区：
文献类型：
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作者：
JAGIELLO, G;FANG, JS
早期（第16天）卵母细胞的二倍体交叉频率显著高于晚期（第18天）卵母细胞的平均值。在年轻或老年成年女性的卵母细胞中，两个年龄段的交叉频率都有所下降，表明交叉缺失和/或终止。晚期卵母细胞中发现的I型单价体数量多于进入二倍体的早期卵母细胞。在23日龄、2个月龄和24个月龄的雄性二倍体精母细胞中，交叉频率没有发现差异。在所研究的所有年龄段中，女性的交叉频率普遍高于男性。
Diplotene chiasma frequencies from early (day 16) fetal oocytes are significantly greater than the average from late (day 18) oocytes. A decrease in chiasma frequencies from both ages was found at diakinesis/MI [metaphase I] in oocytes of young or old adult females, indicating a loss of chiasmata and/or terminalization. A greater number of type I univalents was found in late oocytes than early oocytes entering diplotene. No differences were found in chiasma frequencies of male diplotene spermatocytes studied at 23 days, 2 mo., or 24 mo. of age. A greater chiasma frequency was generally found in the female than the male at all ages studied.