Pulmonary diffusing capacity:: Assessment with oxygen-enhanced lung MR imaging -: Preliminary findings
Pulmonary diffusing capacity:: Assessment with oxygen-enhanced lung MR imaging -: Preliminary findings
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DOI：
10.1148/radiol.2222000869
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发表时间：
2002-02-01
期刊：
影响因子：
19.7
通讯作者：
Reiser, MF
中科院分区：
文献类型：
--
作者：
M端ller, CJ;Schwaiblmair, M;Reiser, MF
目得：为了确定在氧增强磁共振（MR）肺成像在健康志愿者和肺部疾病患者的信号强度（SI）的时间过程中的差异，并将这些差异与肺diffussioncapacity.MATERIALS和METHODS：17例肺部疾病和11名健康志愿者进行氧增强MR成像，而他们呼吸室内空气和100%的氧气。使用具有全局或部分选择性反转脉冲的涡轮自旋回波序列。对于后处理，计算100%氧气呼吸期间的S1斜率图。结果：患者和志愿者的Sl斜率差异有统计学意义（P <0.05，Mann-Whitney U检验）。对于部分选择性反转脉冲（r（2）= 0.81）和全局反转脉冲（r（2）= 0.74），在DLCO和Sl斜率之间检测到线性相关。较低的相关性与部分选择性脉冲的SI变化相关（r（2）= 0.04;全局脉冲，r（2）= 0.81）。在Sl斜率和Sl变化图中可以看到区域差异。这些差异与X光片和计算机断层扫描scanns.CONCLUSION：在呼吸100%氧气的SI斜率允许空间分辨评估肺弥散能力的结果。
PURPOSE: To determine differences in the signal intensity (Sl) time courses at oxygen-enhanced magnetic resonance (MR) lung imaging in healthy volunteers and patients with pulmonary diseases and to correlate these differences with pulmonary diffusing capacity.MATERIALS AND METHODS: Seventeen patients with pulmonary diseases and 11 healthy volunteers underwent oxygen-enhanced MR imaging while they breathed room air and 100% oxygen. A turbo spin-echo sequence with global or section-selective inversion pulses was used. For postprocessing, Sl slope maps during the breathing of 100% oxygen were calculated. Mean Sl slope and Sl change values were compared with the diffusing capacity of the lung for carbon monoxide (DLCO).RESULTS: The Sl slopes were significantly different for patients and volunteers (P less than or equal to .05, Mann-Whitney U test). Linear correlations were detected between the DLCO and Sl slopes for the section-selective inversion pulse (r(2) = 0.81) and the global inversion pulse (r(2) = 0.74). A lower correlation was associated with the Sl change for the section-selective pulse (r(2) = 0.04; global pulse, r(2) = 0.81). Regional differences were seen in the Sl slope and Sl change maps. These differences correlated with findings on radiographs and computed tomographic scans.CONCLUSION: The Sl slope during the breathing of 100% oxygen allows spatially resolved assessment of the pulmonary diffusion capacity.