Trends in psychotropic medication use among US adults
Trends in psychotropic medication use among US adults
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DOI：
10.1002/pds.1367
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发表时间：
2007-05-01
影响因子：
2.6
通讯作者：
Orwig, Denise
中科院分区：
文献类型：
--
作者：
Paulose-Ram, Ryne;Safran, Marc A.;Orwig, Denise
目的 研究非机构化美国成年人处方精神药物使用的趋势和流行率。 方法 对年龄 > 17 岁人群进行的第三次全国健康和营养检查调查（NHANES；1988-1994；n = 20 050）和 1999-2002 NHANES（n = 12 060）的处方药数据进行检查，这两项全国代表性横断面健康检查调查。按年龄调整的精神药物使用率从1988-1994年的6.1%上升到1999-2002年的11.1%（p < 0.001）。这是由于抗抑郁药物的使用增加了三倍以上（1988-1994 年为 2.5%，1999-2002 年为 8.1%（p < 0.001））。所有年龄、性别和种族群体的抗抑郁药物使用时间段之间均出现显着增加，但男性的增加幅度不及女性、非西班牙裔黑人和墨西哥裔美国人的增加幅度低于非西班牙裔白人。从1988-1994年到1999-2002年，抗焦虑/镇静/催眠(ASH)药物(3.5-3.8%)、抗精神病药物(0.8-1.0%)和抗躁狂药物(0.3-0.4%)的使用流行率保持相对稳定。多种精神药物的年龄调整患病率从 1988-1994 年的 1.2% 增加到 1999-2002 年的 3.1% (p < 0.001)。结论 自 1988-1994 年以来，美国成年人精神药物的使用有所增加，特别是抗抑郁药。增幅因性别和种族而异，表明与非西班牙裔白人相比，非西班牙裔黑人和墨西哥裔美国人的男性和女性利用率均不足。 John Wiley & Sons, Ltd 于 2007 年出版。
Purpose To examine trends and prevalence of prescription psychotropic medication use among noninstitutionalized US adults.Methods Prescription medication data from the third National Health and Nutrition Examination Survey (NHANES; 1988-1994; n = 20 050) and the 1999-2002 NHANES (n = 12 060), two nationally representative cross-sectional health examination surveys, were examined for persons aged > 17 years.Results The age-adjusted prevalence of psychotropic medication use increased from 6.1% in 1988-1994 to 11.1% in 1999-2002 (p < 0.001). This was due to more than a three-fold increase in antidepressant use (2.5%, 1988-1994 vs. 8.1%, 1999-2002 (p < 0.001)). Significant increases between time periods for antidepressant use were seen for all age, gender, and race-ethnic groups although increases were less pronounced for males than females and non-Hispanic blacks and Mexican Americans than non-Hispanic whites. Prevalence of use remained relatively constant from 1988-1994 to 1999-2002 for anxiolytic/sedative/hypnotic (ASH) medications (3.5-3.8%), antipsychotics (0.8-1.0%), and antimanic agents (0.3-0.4%). The age-adjusted prevalence of multiple psychotropic medication use increased from 1.2% in 1988-1994 to 3.1% in 1999-2002 (p < 0.001).Conclusions Psychotropic medication use among US adults increased since 1988-1994, specifically of antidepressants. Increases varied by gender and race-ethnicity indicating under-utilization for non-Hispanic blacks and Mexican Americans compared to non-Hispanic whites for both males and females. Published in 2007 by John Wiley & Sons, Ltd.